The urgent requirement for research and producing and characterizing polyclonal and monoclonal antibodies and their relative antigens emphasize the necessity for establishment of Immunochemistry Department.

Sufficient information about the chemical structure of antigens, their binding to other biological materials in addition to their application in immunization of lab animals is required to acquire antigens through different methods i.e. synthesis and purification.

Meanwhile, Immunochemistry Department is also responsible to conduct comprehensive research on chemical reaction, affinity and purification of polyclonal and monoclonal antibodies as well as conjugation of enzyme and fluorescent substances to antibodies, providing buffer and chemical environment to maximize enzyme and antibodies stability as well as offering Epitope Mapping service are achieved at this department.

In summary, other activities of Immunochemistry Department include requirement of purified antigens and antibodies, their binding to enzyme and fluorescent substances used in the quality and quantity analysis of biological processes characterization of an antibody, designation of Epitope Mapping for biological materials, stabilization of antibodies and antigens in different environments, designing various test such as ELISA for specific purposes and application of modern methods for improvement of the test preciseness and quickness.

Filed of Activity:

1. Polyclonal antibody production.
2. Applying different kinds of biochemical procedures to acquire purified antigen
3. Studying the molecular structure of materials in order to produce required polyclonal and monoclonal antibodies
4. Designing Epitope Mapping of protein molecules
5. Verifying the best methods for immunization of different Antigens
6. Discovering the best techniques for purification of produced antibodies
7. Determining the affinity of produced antibodies
8. conjugation of  different substances like enzymes and various fluorescent dyes to antibodies and antigens
9. Performing chemical and enzymatic modifications on antibodies to use them in different cases
10. Using specific purified antibodies for measurement of biological substances.
11. Increasing the stability of antibodies and antigens in different conditions
12. Designing the ELISA kits

Faculty members:

• Dr Mohammad Babashamsi
• Dr Mahmood Jeddi Tehrani
• Dr Hodjatallah Rabbani
• Dr Saeed Talebi  
• Dr Fereshteh Shamsipour
• Roya Ghods
• Mohtaram Vafakhah
• Seyed Ahmad Reza Mahmoodi
• Jafar Mahmoudian